Richard Bucala Selected Research

MSH Release-Inhibiting Hormone (MIF-I)

1/2022

"Near Cure" treatment of severe acute EAE in MIF-1-deficient female and male mice with a bifunctional MHCII-derived molecular construct.

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Richard Bucala Research Topics

Disease

56	Inflammation (Inflammations) 01/2022 - 04/2003
32	Neoplasms (Cancer) 01/2021 - 10/2002
27	Infections 01/2022 - 07/2003
20	Rheumatoid Arthritis 01/2022 - 01/2002
17	Autoimmune Diseases (Autoimmune Disease) 10/2021 - 04/2003
12	Arthritis (Polyarthritis) 01/2022 - 01/2002
12	Atherosclerosis 11/2020 - 03/2003
11	Fibrosis (Cirrhosis) 04/2021 - 10/2004
10	Sepsis (Septicemia) 01/2020 - 01/2002
8	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2019 - 01/2009
8	Reperfusion Injury 01/2018 - 01/2008
8	Wounds and Injuries (Trauma) 03/2017 - 01/2011
7	Hypoxia (Hypoxemia) 11/2019 - 10/2002
7	Malaria 01/2018 - 03/2004
6	Pain (Aches) 01/2022 - 12/2017
6	Hypersensitivity (Allergy) 01/2019 - 04/2009
6	Anemia 01/2016 - 03/2004
6	Ischemia 10/2014 - 12/2009
5	Atherosclerotic Plaque (Atheroma) 11/2020 - 01/2004
5	Necrosis 03/2017 - 04/2003
5	Lung Injury 05/2015 - 04/2003
5	Infarction (Infarctions) 10/2014 - 04/2011
5	Carcinogenesis 10/2012 - 11/2005
5	Type 2 Diabetes Mellitus (MODY) 05/2010 - 06/2002
4	Multiple Sclerosis 01/2022 - 05/2014
4	Acute Lung Injury 01/2019 - 04/2003
4	Septic Shock (Toxic Shock Syndrome) 01/2019 - 01/2002
4	Lung Diseases (Lung Disease) 07/2015 - 07/2010
4	Stroke (Strokes) 10/2014 - 04/2011
4	Pneumonia (Pneumonitis) 07/2014 - 02/2007
4	Glomerulonephritis 01/2011 - 01/2002
4	Nephrogenic Fibrosing Dermopathy 12/2009 - 04/2004
3	Autoimmune Hepatitis 05/2022 - 02/2014
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2022 - 12/2016
3	COVID-19 01/2022 - 10/2020
3	Systemic Scleroderma (Systemic Sclerosis) 01/2021 - 11/2006
3	Liver Diseases (Liver Disease) 01/2021 - 02/2014
3	Non-alcoholic Fatty Liver Disease 01/2021 - 12/2014
3	Acute Kidney Injury (Acute Renal Failure) 09/2020 - 07/2013
3	Endotoxemia 01/2020 - 08/2011
3	Neuralgia (Stump Neuralgia) 03/2019 - 06/2010
3	Alphavirus Infections 01/2019 - 10/2013
3	Myocardial Ischemia (Ischemic Heart Diseases) 01/2018 - 09/2013
3	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2018 - 03/2010
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2017 - 03/2003
3	Hyperoxia 05/2015 - 01/2013
3	Obesity 05/2015 - 01/2010
3	Lung Neoplasms (Lung Cancer) 04/2015 - 08/2008
3	Liver Cirrhosis (Hepatic Cirrhosis) 01/2015 - 10/2011
3	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2012 - 08/2007
3	Pulmonary Fibrosis (Fibrosing Alveolitis) 05/2011 - 04/2006
2	Chronic Disease (Chronic Diseases) 01/2022 - 01/2020
2	Hyperalgesia 01/2022 - 01/2021
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2020 - 06/2010
2	Colitis 01/2020 - 03/2007
2	Cardiomyopathies (Cardiomyopathy) 01/2020 - 12/2013

Drug/Important Bio-Agent (IBA)

156	Macrophage Migration-Inhibitory FactorsIBA 01/2022 - 01/2002
80	CytokinesIBA 05/2022 - 01/2002
26	Proteins (Proteins, Gene)FDA Link 01/2020 - 10/2002
15	ChemokinesIBA 01/2021 - 11/2005
11	GlucocorticoidsIBA 10/2021 - 01/2002
9	dopachrome isomeraseIBA 12/2021 - 08/2008
9	Messenger RNA (mRNA)IBA 01/2021 - 10/2002
8	CollagenIBA 11/2019 - 01/2004
8	Peptides (Polypeptides)IBA 01/2019 - 03/2010
7	Biological ProductsIBA 11/2021 - 12/2006
7	macrophage migration inhibitory factor receptorIBA 01/2021 - 01/2011
6	LigandsIBA 01/2021 - 12/2006
6	Glucose (Dextrose)FDA LinkGeneric 08/2013 - 10/2007
6	Advanced Glycation End ProductsIBA 07/2008 - 06/2002
5	Interleukin-6 (Interleukin 6)IBA 01/2022 - 01/2006
5	AntibodiesIBA 11/2021 - 01/2009
5	Interleukin-8 (Interleukin 8)IBA 01/2021 - 08/2007
5	Matrix Metalloproteinases (MMPs)IBA 01/2020 - 01/2005
5	LipopolysaccharidesIBA 01/2020 - 04/2003
5	DDTIBA 01/2019 - 08/2014
5	Biomarkers (Surrogate Marker)IBA 07/2017 - 05/2010
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 06/2012 - 08/2008
5	Toll-Like Receptors (Toll-Like Receptor)IBA 06/2010 - 11/2005
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2010 - 01/2003
4	HMGB1 Protein (HMG1)IBA 01/2022 - 12/2017
4	Apolipoproteins E (ApoE)IBA 11/2020 - 01/2004
4	Pharmaceutical PreparationsIBA 01/2019 - 06/2010
4	SteroidsIBA 01/2019 - 03/2007
4	Monoclonal AntibodiesIBA 01/2019 - 01/2004
4	Peptide Hydrolases (Proteases)FDA Link 10/2018 - 06/2012
4	AntigensIBA 01/2018 - 07/2003
4	Phosphotransferases (Kinase)IBA 04/2011 - 10/2002
3	Interleukin-23 (Interleukin 23)IBA 01/2022 - 01/2018
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 01/2013
3	Interleukin-17 (Interleukin 17)IBA 01/2022 - 01/2019
3	Antiviral Agents (Antivirals)IBA 11/2019 - 01/2009
3	Interleukin-12 (IL 12)IBA 01/2018 - 04/2003
3	Immunoglobulin G (IgG)IBA 01/2018 - 07/2003
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2013 - 12/2004
3	GadoliniumIBA 12/2009 - 10/2007
3	Interferon-gamma (Interferon, gamma)IBA 04/2009 - 04/2003
2	MIF098IBA 11/2019 - 10/2018

Therapy/Procedure

15	Therapeutics 11/2021 - 04/2003
3	Transplantation 01/2019 - 06/2012